Former Congressman Pat Toomey, who served as the head of the Club for Growth for several years, is running in blockbuster race challenging former Republican Arlen Specter, who's recent switch to the Democrats has given them a 60 vote filibuster proof majority in the US Senate. Help Pat Toomey retake the Pennsylvania Senate seat for Republicans!

John Kennedy is the Republican State Treasurer of Louisiana running for U.S. Senate, challenging Democrat Mary Landrieu.

Some recent polls have this race within striking distance for Kennedy, which could give the GOP a key Senate seat in a tough cycle. Help make a difference, and keep the red tide in Louisiana rolling on, by helping John Kennedy fight take Mary Landrieu's Senate seat.

Tim Carnes is running against U.S. Sen. Lindsey Graham in the South Carolina Republican primary.

U.S. Sen. Elizabeth Dole, R-North Carolina, is running for reelection

U.S. Sen. James Inhofe, R-Oklahoma, is running for reelection

U.S. Sen. Gordon Smith, R-Oregon, is running for reelection

U.S. Sen. Lindsey Graham, R-South Carolina, is running for reelection

U.S. Sen. Lamar Alexander, R-Tennessee, is running for reelection

U.S. Sen. Mike Enzi, R-Wyoming, is running for reelection

U.S. Sen. John Barrasso, R-Wyoming, is running for reelection